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Quantum indeterminacy ^f1efcf

  • Uncertainty Principle, e.g. electron cloud, radioactive decay
  • At the quantum scale (sneeze)
  • About individual particles
  • Inherent unpredictability of specific behavior

Chemical reaction

  • E.g. electron orbital changes, binding affinities, reaction rates
  • At the molecular scale (glacier)
  • About interaction & bonds
  • Movement of electrons / transition between states
    • Governed by potential energy landscape → reliable & reproducible
    • Not certainty, but known probabilities
    • Biochemical processes
      • Highly structural & biased (geometric fit)
      • Thermal noise (classical particles collision) dominates

Mutations

  • Non-quantum
    • DNA polymerase errors (thermal/statistical)
    • Chemical instability
    • Radiation (cause classical damage)
    • Chemical mutagens
    • Transposons or viruses
  • Quantum: Proton tunneling (tautomer shifts), rare

In systems with no mechanisms of amplification

  • Statistically averaged out by sheer number
  • Decoherence by interaction with the environment

Magnitude comparison

EventDomainTimescaleAnalogy
Orbital periodQuantum10⁻¹⁶ s1 second
Electron transitionQuantum10⁻¹⁵ s10 seconds
Molecular vibrationMolecular10⁻¹³ (to 10⁻¹² s)17 minutes
Bond break/formChemical10⁻¹² (to 10⁻⁹ s)116 days
Enzymatic reactionBiochemical10⁻⁶ s (to 10⁻³ s)300 years
Neural spikeNeurophysiological10⁻³ s30000 years
  • Nuclear (atomic) rearrangement in slow
  • Transitional state & energy barrier crossing is slow

Structured processes + uncertainties (may amplify)
Comparable to trends vs fluctuations in Commonalities & Differences

  • Scaffold of macroscopic orders
    • Governed by well-understood laws (rate constants, population dynamics)
    • Statistically structured, not clockwork deterministic
    • Interconnected, dynamic, complex causal networks
  • Embedded fluctuations
    • Multiple levels (quantum, thermal, chemical)
    • Not dominant most of the time, but not negligible
  • Mechanisms of amplification
    • Thresholds (neuron firing, developmental)
    • Positive feedback loop (hormonal cascades)
    • Digital coding (DNA single mutation)

Meta-critique: Categorical Thinking?

  • Divisions are
    • Not ontologically distinct, arbitrary to some extent
    • E.g. “quantum vs classical,” “thermal vs biological noise,” “signal vs amplification”
  • Modeling convenience
    • We filter reality through representations
    • Useful in the right context: clarify, explain, predict