Genome ≈ book/recipe ≠ blueprint analogy

  • Genes are 1D digital codes, like text (set of letters for variable length of info)
  • Blueprints are 2D maps, and are too literal for genetics, because each part of a blueprint makes an equivalent part of the machine or building; each sentence of a recipe book does not make a different mouthful of cake

Division of labor between DNA/protein

The word was not DNA. That came afterwards, when life was already established, and when it had divided the labour between two separate activities: chemical work and information storage, metabolism and replication.

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Gene regulation is dynamic & constant

They had carefully arranged the two so that the volado gene only worked when the heat-shock gene was on. At cool temperatures, the flies could not learn. Three hours after a heat shock, however, they suddenly became good learners. A few hours after that, as the heat shock faded into the past, they again lost the ability to learn.

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